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EpiCypher
This antibody meets EpiCypher’s “CUTANA Compatible” criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated approach using EpiCypher optimized protocols (epicypher.com/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. CHD4 is a member of the nucleosome remodeling and deacetylase (NuRD) complex. Within the complex, CHD4 remodels chromatin by deacetylating histones [1]. CHD4 antibody produces CUT&RUN peaks above background (Figure 1) within gene promoters, intergenic, and intronic regions (Figures 1-2).
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