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Custom Services for Reduced Representation Hydroxymethylation Profiling

Zymo Research

Catalog Code: SERV-002Product Unit:
POA

This service is for genome-wide profiling of 5-hydroxymethylcytosine in DNA at single-nucleotide resolution. RRHP also allows strand-specific determination of the location of the 5-hmC modification as well as quantification of 5-hmC levels. Data from RRHP is easily integrated with DNA methylation data from Methyl-MiniSeq™, allowing for direct comparison of DNA methylation and hydroxymethylation in the same sample. Omission of chemical conversion processes allows for both low DNA input as well as straightforward SNP detection.

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