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JUN/c-Jun CUTANA CUT&RUN Antibody

Catalog Code: 13-2019Product Unit: 100µL
POA

This antibody meets EpiCypher’s “CUTANA Compatible” criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated approach using EpiCypher optimized protocols (epicypher.com/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. JUN/c-Jun heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex and binds to the AP-1 consensus motif [1]. JUN/c-Jun antibody produces CUT&RUN peaks above background primarily in intronic, intergenic, and promoter regions (Figure 1) that overlap with known JUN/c-Jun DNA-binding motifs (Figure 2).

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