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Seraseq ctDNA Complete Reference Material

To further accelerate the validation and clinical application of liquid biopsy-based ccfDNA targeted NGS assays, SeraCare has developed the Seraseq ctDNA Complete that expands coverage of all relevant variant types (SNVs, INDELs, CNVs, and gene fusions) in a single, highly multiplexed reference sample. These new products are offered in either a purified ctDNA format or a plasma-like matrix format, all precisely quantitated by digital PCR against a single well-characterized genomic background (GM24385), and orthogonally validated with NGS technology.

25 unique multiplexed variants in 16 genes, covering 12 SNVs, 7 INDELs, 3 CNVs, and 3 SVs, in purified and plasma-like matrix formats
6 different allele frequencies (AF) – WT, 0.1%, 0.5%, 1%, 2.5% and 5%
Allows end-to-end evaluation of assay performance across the entire workflow, including pre-analytic extraction steps
Variants quantitated with digital PCR and orthogonally validated by NGS
Blends with well-characterized GM24385 human genomic DNA as background ‘wild-type’ material

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Seraseq ctDNA Complete Reference Material WT
Catalog Code: 0710-0674
Product Unit: 1 x 5mL $1,450.00
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Seraseq ctDNA Complete Reference Material AF0.1%
Catalog Code: 0710-0673
Product Unit: 1 x 5mL $1,747.00
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Seraseq ctDNA Complete Reference Material AF0.5%
Catalog Code: 0710-0672
Product Unit: 1 x 5mL $1,747.00
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Seraseq ctDNA Complete Reference Material AF1%
Catalog Code: 0710-0671
Product Unit: 1 x 5mL $1,747.00
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Seraseq ctDNA Complete Reference Material AF2.5%
Catalog Code: 0710-0670
Product Unit: 1 x 5mL $1,747.00
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Seraseq ctDNA Complete Reference Material AF5%
Catalog Code: 0710-0669
Product Unit: 1 x 5mL $1,747.00
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