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Seraseq MSI Reference Panel Mix

LGC SeraCare has developed microsatellite instability (MSI) reference materials containing the key mono- and dinucleotide biomarkers typically analyzed in molecular MSI assays – NR-21, NR-24, BAT-25, BAT-26 and MONO-27. These markers are blended at two different allele frequency levels – AF5% and AF20% - to support MSI assay LoD determinations and accurate MSI detection. These products are offered as tumor-normal matched pairs, with variants precisely quantitated by digital PCR as well as qPCR/CE against a highly characterized genomic DNA from a background WT cell line (GM24385) determined as microsatellite stable (MSS).

Plasmid-based spike-ins of 5 key MSI biomarkers typically analyzed in molecular assays that measure MSI in cancer patent samples
Offered as tumor-normal matched pairs per AF level
Each biomarker blended at two AF levels – 5% and 20% - to support assay LoD determinations and accurate MSI detection in patient samples
Variant AFs quantitated by ddPCR and qPCR assays
Normal background DNA is a highly characterized GM24385 human genomic DNA known to be microsatellite stable (MSS)

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Seraseq MSI Reference Panel Mix AF5%
Catalog Code: 0710-1675
Product Unit: 2 x 15µL (20ng/µL) $1,323.00
Excl. GST

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Seraseq MSI Reference Panel Mix AF20%
Catalog Code: 0710-1676
Product Unit: 2 x 15µL (20ng/µL) $1,323.00
Excl. GST

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