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Captify Nucleosome Full Panel

Catalog Code: 16-9001Product Unit: 96 well plate
POA

Understanding epigenetic reader proteins and their binding preference for post-translational modifications (PTMs) is key to unveiling how these proteins regulate genome processes and how their dysregulation may be contributing to disease. The Captify™ Nucleosome Panel enables access to epigenetic diversity in a physiologically relevant context, the nucleosome, where chromatin reader activity can be accurately interrogated. The 96-well plate contains recombinant mononucleosomes as well as appropriate controls. Human histones expressed in E. coli bearing single and combinatorial histone post-translational modifications (PTMs) are wrapped by 147 or 199 base pair DNA with a 5’ biotin-TEG group and a central 601-positioning sequence, identified by Lowary and Widom

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