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H3K36me2 CUTANA™ CUT&RUN and CUT&Tag Antibody

Catalog Code: 13-0056Product Unit: 100µg
POA

This H3K36me2 antibody is validated for chromatin profiling of histone H3 lysine 36 dimethylation (H3K36me2), an epigenetic mark deposited primarily by the histone methyltransferase NSD2 (WHSC1/MMSET). H3K36me2 is broadly enriched downstream of transcription start sites across gene bodies and intergenic chromatin, where it contributes to chromatin accessibility, transcriptional regulation and enhancer activity. Dysregulation of NSD2-mediated H3K36me2 deposition drives oncogenic transcriptional programs in multiple cancers, making H3K36me2 antibodies essential tools for studying NSD2 biology and epigenetic drug discovery.

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