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Nucleosome, Recombinant Human, H2AK5,9,13,15ac dNuc, Biotinylated

EpiCypher

Catalog Code: 16-0376Product Unit: 50µg
POA

Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3.1-P68431; H4-P62805) wrapped by 147 base pairs of 601 positioning sequence DNA. Histone H2A (created by a proprietary semi-synthetic method) contains acetylated lysines at positions 5, 9, 13, and 15. The nucleosome is the basic subunit of chromatin. The 601 sequence, identified by Lowary and Widom, is a 147-base pair sequence that has high affinity for histone octamers and is useful for nucleosome assembly and contains a 5�� biotin-TEG group.

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